The Kemtrak UV Spectra Process Analyzer from South Fork Instruments represents a significant advancement in real-time process monitoring technology for bioprocessing applications. This multi-wavelength deep-UV photometer is specifically designed for continuous absorbance measurement of proteins, peptides, polypeptides, mRNA/DNA, amino acids, active pharmaceutical ingredients, and process intermediates across the 190 to 440 nm spectrum. The analyzer's capabilities support critical applications in chromatography, filtration, biochemical production, and comprehensive process monitoring.
John Daly, Technical Director at South Fork Instruments, emphasized the growing demands on bioprocessing teams, stating that they are working with higher concentrations and more demanding purification steps than ever before. The Kemtrak UV Spectra addresses these challenges by providing deep-UV performance, zero-dead-volume measurement, and verification tools necessary for generating reliable inline data. Its stability and real-time multi-wavelength capability make it particularly suitable for chromatography, filtration, and high-value process streams where precision monitoring is essential.
Technical specifications reveal the analyzer's sophisticated capabilities, including high-stability optical measurement with up to 10 user-selectable wavelengths, ±0.005 AU photometric resolution, and a 10 Hz sampling frequency for continuous real-time monitoring. To ensure accurate inline measurement, the system integrates zero-dead-volume hygienic measurement cells available in multiple materials including stainless steel, titanium, Hastelloy, Monel, PTFE, and PPSU, with window options in sapphire and UV-fused silica. These wetted surfaces feature electropolished finishes down to Ra _ 0.38 μm, enhancing measurement precision and reliability.
Key features distinguishing the Kemtrak UV Spectra include its multi-wavelength deep-UV absorbance measurement from 190–440 nm with up to 10 user-selectable wavelengths, high-resolution continuous measurement with ±0.005 AU photometric resolution and fast 10 Hz sampling, zero-dead-volume hygienic measurement cells in multiple wetted materials for rapid response inline monitoring, a mercury-free UV-xenon light source capable of up to two years of continuous operation, and integrated traceable verification with NIST-compliant reference standards and verification port. This comprehensive feature set positions the analyzer as a robust solution for demanding bioprocessing environments.
The introduction of the Kemtrak UV Spectra expands South Fork's instrumentation lineup for chromatography, filtration, and real-time process monitoring by adding a specialized deep-UV measurement option. This development comes at a time when bioprocessing operations require increasingly sophisticated monitoring solutions to ensure product quality and process efficiency. The analyzer's ability to provide real-time data on critical process parameters represents an important advancement for industries relying on precise biochemical production and purification processes. For additional information about the analyzer and its configuration options, visit https://www.southforkinst.com.
